DsiRNA was delivered in mice via IT injection using i-Fect. This added further support to the idea that the very potent DsiRNA coupled with a cationic delivery system that works in neurons is a very effective way to study the role of various genes in CNS function.
By Pete Shuster
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Posted in DsiRNA, Synaptic Transmissiom, featured researchers, i-Fect Transfection Kits
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Also tagged 27mer DsiRNA, Add new tag, Delivering DsiRNA, Deliverying siRNA in vivo, Dr. Jeffrey Mogil, Dr. Mark Behlke, Gene Expression, Gene Silencing Methods, intrathecal delivery of siRNA
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September 29, 2008 – 1:05 pm
Shedding Light on New Pain Pathways
There is no joy in Painville. Our answer to pain is: “make it go away”! It spoils quality of life. The socio-economic costs for treatments, loss of productivity and absenteeism, are measured in billions USD$.
Today, moderate to severe pain is treated mostly with NSAIDs, narcotics or tricyclics (anti-depressants). Properly prescribed, [...]
By Pete Shuster
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Posted in DsiRNA, Pain Research, People, featured researchers
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Also tagged APJ, CCR2, Chronic Pain, i-Fect, morphine, Neurotensin Receptors, Nociceptive Pain, non-Narcotics, non-Opioid Pain Pathway, NTS2, Opioid Receptors, opioidergic-independent pathways, Pain Pathways, Pain Therapies, University of Sherbrooke
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September 14, 2008 – 2:11 pm
Neuromics has been helping researchers make “gains on pain” from day one. Our initial sales were Opioid Receptor Antibdies licensed from Dr. Robert Elde’s lab at the University of Minnesota.
From this start, we have expanded our expertise and products. Our reputation in this area has resulted in our forming collaborations and friendships with research teams doing [...]
By Pete Shuster
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Posted in Uncategorized
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Also tagged Chronic Pain, Dr. Nicolas Beaudet, morphine, Neurotensin Receptors, Nociceptive Pain, NTS-1, NTS-2, NTS-3, Opiates, Opioid Receptors, Opioids
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Dr. Mark Behlke and 27mer DsiRNAs
I am pleased to be featuring Dr. Mark Behlke’s story as our first. This was an easy choice because our main characters, Mark and the 27mer DsiRNAs (Dicer Substrate Small Interfering RNAs), are rising stars in small interfering (siRNA) based research.
siRNAtechnology addresses the need for Biosciences Researchers and Clinicians [...]
By Pete Shuster
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Posted in DsiRNA, People, Stories, featured researchers
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Also tagged 21mer siRNA, 27mer DsiRNA, Dicer Complex, Dicerna Pharmaceuticals, Dr. Dongho Kim, Dr. John Rossi, Dr. Mark Behlke, Gene Expression, Gene Silencing, Integrated DNA Technologies, NTS2 Gene, Pain Modulation, RISC, University of Sherbrooke
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