DsiRNA was delivered in mice via IT injection using i-Fect. This added further support to the idea that the very potent DsiRNA coupled with a cationic delivery system that works in neurons is a very effective way to study the role of various genes in CNS function.
Story to be published July 11, 2008.
Dr. Behlke, his team and collaborators are working on improving the delivery of Dicer-substrate siRNAs (DsiRNAs) in vitro and in vivo.
His work has helped establish siRNA technology as a viable tool for drug development.
Please see the article titled RNAi Researchers Galvanized by Advances: Technology’s Viability in Drug Development Is [...]
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