Monthly Archives: July 2008

Spinal Cord Injury and Ependymal Cells

This research sheds light on the natural regeneration that occurs in the area of damaged spinal cord tissue. The surprise here is the role that Edendymal Progenitor Cells are playing in repair mechanism vs Neural Stem Progenitors. 
In this publication, researchers have employed genetic fate mapping to characterize a candidate neural stem cell population in the adult spinal cord [...]

Dr. Steve Stice Podcast

This Podcast gives is a good primer on Embryonic Stem Cells (ESCs)…where they come from, how they are used and the promise they have for helping researchers cure human diseases.

The listener will gain insight how ECSs when manipulated into mature neuron cell lines can accelerate the pace of neurological research for scientists working on treatments for spinal cord injuries and neurological diseases such as Parkinson’s, Huntington’s, Alzheimer’s, ALS and possibly even depression

On Deck-Dr. Steve Stice

We read about the promise of stem cells in the news every day. They could prove to be ”magic bullets” for curing diseases like Alzheimer’s. Parkinson’s, MS and others. Stem Cell Research is also surrounded with controversy as currently cells are often harvested from human embryos and fetuses.I believe top researchers will prove to be the voice of reason in the [...]

Improving 27mer DsiRNA Preformance

The DsiRNA story marches forward with yet another important publication. We will give you an opportunity to upload the fulltext article at the end of this posting.
Dr. Mark Behlke, Dr John Rossi and team have been gaining deeper understanding of the Mechanism of Dicer-substrate small-interfering RNA (DsiRNA) processing. This understanding is leading to better and [...]

More Good News for DisRNA Research

As a follow on to the potential of 27mer DsiRNAs as a key platform for drug discovery and development, we are happy to report:
15.07.2008 13:34
Dicerna Pharmaceuticals, a Second Generation RNA Interference Company, Completes Second Closing of Series A Financing; Unveils Strategic Focus
Dicerna Pharmaceuticals, Inc. (www.dicerna.com), an RNA interference company developing novel therapeutics utilizing proprietary [...]

The First Story is Here!

Dr. Mark Behlke and 27mer DsiRNAs
 
I am pleased to be featuring Dr. Mark Behlke’s story as our first. This was an easy choice because our main characters, Mark and the 27mer DsiRNAs (Dicer Substrate Small Interfering RNAs), are rising stars in small interfering (siRNA) based research.
 
siRNAtechnology addresses the need for Biosciences Researchers and Clinicians [...]

Dr. Behlke’s 27mer DsiRNA Story Coming Soon

Learn the News Behind the News on 27mer DsiRNA. Includes the story of the how the potentcy of 27mer siRNA was discovered and exiting developments regarding the understanding of the role of the Dicer Complex and RISC. Also featured will be advances in 27mer oligo design and how the technology is being used in basic research and [...]