Category Archives: People

The Quest for Better Pain Therapies

January 15, 2009 – 7:18 pm

G- protein coupled receptor (GPCR) and Drug Responsiveness

About Dr. Laura Bohn 
 Background:
Spring 2009-Associate Professor (tenured) at The Scripps Research Institute, Department of Molecular Therapeutics, Jupiter, FL.
10/2007- Associate Professor (tenured), The Ohio State University College of Medicine, Departments of Pharmacology and Psychiatry, Program in Pharmacogenomics

8/2003-9/2007 Assistant Professor, The Ohio State University College of Medicine,
1/1999–8/2003 Post-Doc/Assistant Research Professor. [...]

By Pete Shuster | Also posted in Pain Research, Stories, featured researchers | Tagged , , , , , , , , , , , , , | Comments (0)

Featuring Dr. Laura Bohn

December 25, 2008 – 10:05 pm

January’s Story: Decoupling GPCR Pain Therapies from Destructive Side Effects. 
We are pleased to have Dr. Laura Bohn as our “coming soon” featured researcher. 
She caught my attention when she referenced one of our  Opioid Receptor Antibodies in the publication: C. E. Groer, K. Tidgewell, R. A. Moyer, W. W. Harding, R. B. Rothman, T. E. Prisinzano, and L. M. Bohn. An [...]

By Pete Shuster | Also posted in Pain Research, Stories, featured researchers | Tagged , , , , , , , | Comments (0)

Isolating and Maintaining Embryonic Stem Cells

December 3, 2008 – 6:24 pm

I have featured Steve Stice and his team at ArunA Biomedical and UGA. They are pioneers in developing Embryonic Stem Cell Based Cultures and Assays for Drug Discovery and Basic Research. Given the importance of their work, I am commited to keeping my finger on the pulse of their advances and discoveries.
Here they isolate, and maintain in [...]

By Pete Shuster | Also posted in Companies, Stem Cell Research, featured researchers | Tagged , , , , , , | Comments (1)

Making Connections that Count

November 24, 2008 – 8:50 pm

Building Neuroscience Value Networks
For this month’s backstory, I am excited to introduce Dr. Ijad Madisch and the Networking Site he founded, ResearchGATE corporation (www.researchgate.net). 
Madisch, 27, an M.D. and Ph.D. virologist, says he and some friends came up with the idea when he moved from his native Germany for a research traineeship at Harvard Medical School in [...]

By Pete Shuster | Also posted in Stories | Tagged , , , , , | Comments (0)

The Sensory and Autonomic Side of Spinal Cord Injury

October 26, 2008 – 9:11 am

About Dr. Matt Ramer

2001-Present-Associate Professor-University of British Columbia and ICORD
Post Doc-King’s College London
PhD.-Physiology-Queen’s College Kingston, Ontario

Matt Ramer Website
Awards and Funding
Email: ramer@icord.org
Lab Members: A. Gaudet, J. Inskip, A. Scott, L. Soril
Finding Fixes for Injured Nerves
I first became aware of Matt’s research in early 2005. This was catalyzed when he kindly shared excellent IHC images his lab [...]

By Pete Shuster | Also posted in Pain Research, Stories, featured researchers | Tagged , , , , , , , , , , , , , , , , , , , , | Comments (0)

ACIC3 Receptors Knockdown in vivo

October 19, 2008 – 2:06 pm

Researchers using siRNA complexed with our i-Fect ™ transfection regent have successfully knocked down ASIC3 Receptors in vivo. This publication joins the growing parade (starting with Luo et al, 2005) that reference successful modulation of receptors involved in pain using siRNA complexes. These studies all share animal behavior studies showing a marked change in response to pain [...]

By Pete Shuster | Also posted in Pain Research | Tagged , , , , , , | Comments (0)

Dr. Matthew Ramer, Neural Regeneration and SCI

October 16, 2008 – 9:42 am

I dream of the day that people suffering from spinal cord injuries (SCIs) will be restored to full function. The good news is there are researchers and dedicated centers that form the back-bone of SCI repair research.
I am excited and honored to be featuring Dr. Matthew Ramer for this month’s backstory. Matt is a member of ICORD (International Collaboration On [...]

By Pete Shuster | Also posted in Uncategorized, featured researchers | Tagged , , , , , , , , , | Comments (0)

Dr. Philippe Sarret Team and Potential New Pain Targets

September 29, 2008 – 1:05 pm

Shedding Light on New Pain Pathways

There is no joy in Painville. Our answer to pain is: “make it go away”! It spoils quality of life. The socio-economic costs for treatments, loss of productivity and absenteeism, are measured in billions USD$.
Today, moderate to severe pain is treated mostly with NSAIDs, narcotics or tricyclics (anti-depressants). Properly prescribed, [...]

By Pete Shuster | Also posted in DsiRNA, Pain Research, featured researchers | Tagged , , , , , , , , , , , , , , , | Comments (0)

Umbilical-Cord Matrix Stem Cells and Cerebral Ischemia

September 11, 2008 – 2:20 pm

I am winding down on the stem cell story for now as later in the month I will be featuring my good friends at University of Sherbrooke and their research in the area of chronic pain.
I did want to highlight yet another potential application for stem cells. For this, we send kudos to Dr. Yan Xu [...]

By Pete Shuster | Also posted in Stem Cell Research | Tagged , , , , , , , , , , | Comments (0)

On Deck-Dr. Steve Stice

July 21, 2008 – 8:00 pm

We read about the promise of stem cells in the news every day. They could prove to be ”magic bullets” for curing diseases like Alzheimer’s. Parkinson’s, MS and others. Stem Cell Research is also surrounded with controversy as currently cells are often harvested from human embryos and fetuses.I believe top researchers will prove to be the voice of reason in the [...]

By Pete Shuster | Also posted in Stem Cell Research, Uncategorized, featured researchers | Tagged , , , , , , , | Comments (2)