October 1, 2008 – 7:52 pm
Just wanted to update you on my friends at Dicerna…from in vivo blog…
Wednesday, October 31, 2007
Dicerna Crashes RNAi Party
Life often imitates art, as the saying goes.
In “This Is Spinal Tap,” the classic rock and roll mockumentary chronicling the eponymous band, guitarist Nigel Tufnel famously brags that his amplifiers, unlike conventional ones that max out at [...]
September 29, 2008 – 1:05 pm
Shedding Light on New Pain Pathways
There is no joy in Painville. Our answer to pain is: “make it go away”! It spoils quality of life. The socio-economic costs for treatments, loss of productivity and absenteeism, are measured in billions USD$.
Today, moderate to severe pain is treated mostly with NSAIDs, narcotics or tricyclics (anti-depressants). Properly prescribed, [...]
By Pete Shuster
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Also posted in DsiRNA, Pain Research, People
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Tagged APJ, CCR2, Chronic Pain, Dr. Philippe Sarret, i-Fect, morphine, Neurotensin Receptors, Nociceptive Pain, non-Narcotics, non-Opioid Pain Pathway, NTS2, Opioid Receptors, opioidergic-independent pathways, Pain Pathways, Pain Therapies, University of Sherbrooke
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August 31, 2008 – 10:53 am
Dr Steve Stice and Human Stem Cells
I am pleased and honored for the privilege of profiling Dr. Steve Stice. He has a history of working in areas that are Biotechnology Headliners…from cloning to stem cells. Here I will be focusing on his current work with Human Stem Cells and Neural Progenitors at ArunA Biomedical and [...]
We read about the promise of stem cells in the news every day. They could prove to be ”magic bullets” for curing diseases like Alzheimer’s. Parkinson’s, MS and others. Stem Cell Research is also surrounded with controversy as currently cells are often harvested from human embryos and fetuses.I believe top researchers will prove to be the voice of reason in the [...]
The DsiRNA story marches forward with yet another important publication. We will give you an opportunity to upload the fulltext article at the end of this posting.
Dr. Mark Behlke, Dr John Rossi and team have been gaining deeper understanding of the Mechanism of Dicer-substrate small-interfering RNA (DsiRNA) processing. This understanding is leading to better and [...]
Dr. Mark Behlke and 27mer DsiRNAs
I am pleased to be featuring Dr. Mark Behlke’s story as our first. This was an easy choice because our main characters, Mark and the 27mer DsiRNAs (Dicer Substrate Small Interfering RNAs), are rising stars in small interfering (siRNA) based research.
siRNAtechnology addresses the need for Biosciences Researchers and Clinicians [...]
By Pete Shuster
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Also posted in DsiRNA, People, Stories
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Tagged 21mer siRNA, 27mer DsiRNA, Dicer Complex, Dicerna Pharmaceuticals, Dr. Dongho Kim, Dr. John Rossi, Dr. Mark Behlke, Dr. Philippe Sarret, Gene Expression, Gene Silencing, Integrated DNA Technologies, NTS2 Gene, Pain Modulation, RISC, University of Sherbrooke
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